中国医学科学院/北京协和医学院病原生物学研究所党委副书记、纪委书记、课题组组长。全国结核病防治综合质量控制专家指导委员会委员、中国免疫学会感染免疫分会委员、中国防痨协会结核病基础专业分会常委。《中华结核和呼吸杂志》和《结核与肺部疾病杂志》编委。
主要研究方向是感染、炎症与免疫机制研究。主持或参与国家科技重大专项、国家重点研发计划、国家自然科学基金、医学与健康科技创新工程等多项国家级和院校级科研项目，参与多项战略咨询项目研究。在SCI收录杂志上发表学术论文30余篇；获得6项发明专利授权；获得中华医学科学技术奖二等奖（排名第五）、重大专项创新团队奖。

结核病等我国重大传染病免疫机制及新型生物标识的研究。

1.    国家重点研发计划（2021-2026），结核病新型诊断、治疗、干预手段及产品研发，课题骨干。
2.    中国医学科学院中央级公益性科研院所基本科研业务费（2020-2022），西藏自治区结核病流行菌株特征及致病特点研究，课题负责人。
3.    国家自然科学基金委员会面上项目（2021-2024），血管生成素2参与活动性肺结核免疫机制研究，课题负责人。
4.    中国工程院咨询研究项目(2019-2020 )，中国与法国等发达国家结核病防治体系的对比研究，课题骨干。
5.    国家外专局高端外国专家项目(2018-1019)，结核病新型分子标识研究，课题负责人。
6.    国家科技重大专项 (2017-2020)，菌阴结核病和结核分枝杆菌潜伏感染相关生物标志物研究，子课题负责人。
7.    中国医学科学院医学与健康科技创新工程项目(2016-2021)，感染性疾病（结核病等）诊治新策略研究，课题骨干。
8.    国家自然科学基金委员会面上项目(2012-2015)，接头蛋白Gab2调控结核病发生、发展的免疫学功能研究，课题负责人。
9.    国家科技重大专项 (2012-2015)，结核病分子标识的研究，课题负责人。
10.    国家科技重大专项(2008-2010)，结核病免疫保护机制研究，课题负责人。
11.    国家科技重大专项 (2008-2010)，结核病诊断分子标识研究，子课题负责人。

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培养博士研究生4名，硕士研究生4名，3名硕士研究生在读。